(For a Reuters live blog on U.S., UK and European stock markets, click LIVE/ or type LIVE/ in a news window)
* Britons warned against international travel
* Kingfisher jumps on strong full-year results
* AstraZeneca vaccine safe, effective - new trial data
* FTSE 100 up 0.3%, FTSE 250 adds 0.2% (Updates to close, adds comments)
By Shivani Kumaresan and Amal S
March 22 (Reuters) - London's FTSE 100 index ended higher on Monday on a weaker pound and as gains in defensive stocks outweighed declines in commodity-linked and travel shares, while drugmaker AstraZeneca jumped on upbeat U.S. trial results.
The FTSE 100 index .FTSE recouped its early losses and ended 0.3% higher, with dollar-earning consumer staples stocks, including Unilever ULVR.L , Reckitt Benckiser Group RB.L , British American Tobacco (JO: SNHJ ) BATS.L and Diageo Plc DGE.L gaining between 0.3% and 2,5%, on the weaker pound.
Healthcare stocks were also among the biggest gainers, with AstraZeneca AZN.L up 3.3% after the drugmaker's COVID-19 vaccine was found 79% effective in a large U.S. trial at preventing symptomatic illness, and was 100% effective against severe or critical disease and hospitalisation. travel and leisure stocks .FTNMX5750 were among the top fallers.
British Airways-owner IAG ICAG.L , down 5.2%, was the biggest faller in the index after social care minister Helen Whately warned that Britons should wait before booking summer holidays abroad, pointing out that there were rising COVID-19 infection rates in Europe. risk, and one being increasingly acknowledged by government ministers, is this summer is even worse than last for the travel space as the UK keeps restrictions in place to avoid undermining its hard-won success with the vaccine," said Russ Mould, AJ Bell investment director.
The FTSE 100 has rebounded nearly 37% from a coronavirus-driven crash last year on vaccine-led optimism, but has struggled to reach pre-pandemic highs as commodity prices, lockdown measures and rising U.S. bond yields weigh.
The domestically focused mid-cap FTSE 250 index .FTMC gained 0.2%, supported by tech and bank stocks.
Home improvement retailer Kingfisher KGF.L rose 3.6% to the top of the blue-chip index, after posting a 44% jump in full-year profit driven by the popularity of do-it-yourself projects during the pandemic.
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