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* GSK hits 15-week low on profit miss
* Barclays falls as loan loss provisions grow
* Next jumps on posting smaller-than-feared slump in sales
* Consumer, tech stocks weigh on mid-cap index
* FTSE 100 up 0.04%, FTSE 250 down 0.2% (Updates to close)
By Sagarika Jaisinghani and Susan Mathew
July 29 (Reuters) - The FTSE 100 ended flat on Wednesday as investors held out for more stimulus from the U.S. Congress and the Federal Reserve, while GlaxoSmithKline, Barclays and Taylor Wimpey slid on weak quarterly earnings.
The world's largest vaccine maker, GSK GSK.L , slumped 3.2% to hit a 15-week low after missing second-quarter profit estimates under the effect of coronavirus lockdowns, dragging the healthcare index .FTNMX4570 down 1.8%. off the quarterly earnings season for UK banks, Barclays BARC.L set aside a higher-than-expected 1.6 billion pounds ($2.07 billion) to cover a possible rise in loan losses due to the COVID-19 pandemic. Its shares fell 6.1%. a 7.7% jump for Next Plc NXT.L helped the blue-chip FTSE 100 .FTSE end in positive territory as the retailer reported a smaller-than-feared slump in second-quarter sales. mid-cap FTSE 250 .FTMC was off 0.2%, weighed by losses in consumer discretionary, financial and tech-related stocks.
The Fed is expected to sound reassuringly accommodative at its policy review due at 2 p.m. ET (1800 GMT), followed by Chair Jerome Powell's press conference, but investors have turned wary over political wrangling between U.S. Democrats and Republicans on a coronavirus relief plan. MKTS/GLOB .N
"Not much will come of (the Fed meeting) in terms of policy. That said, we think a sober assessment from the Fed or Powell could challenge risk sentiment," said Mazen Issa, senior FX strategist at TD Securities.
"With COVID cases ravaging the U.S. and the job market stalling, there is a risk that Powell sounds more bearish than dovish."
Uncertainty about global efforts to contain the pandemic stalled a three-month rally for the FTSE 100 in July. Although recent economic data has shown a revival in business activity with the lifting of nationwide lockdowns, traders are concerned about the damage from another possible shutdown. Taylor Wimpey Plc TW.L shed 8.1% on saying it expected to complete around 40% fewer homes in 2020.
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