Arvinas, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. The company engineers proteolysis targeting chimeras (PROTAC) targeted protein degraders that are designed to harness the body’s own natural protein disposal system to degrade and remove disease-causing proteins. Its product pipeline includes Bavdegalutamide and ARV-766, investigational orally bioavailable PROTAC protein degraders for the treatment of men with metastatic castration-resistant prostate cancer, which are in Phase 1/2 clinical trials; and ARV-471, an orally bioavailable estrogen receptor degrading PROTAC targeted protein degrader for the treatment of patients with locally advanced or metastatic estrogen receptor+/human epidermal growth factor receptor 2-breast cancer, which is Phase 3 clinical trial. Arvinas, Inc. has collaborations with Pfizer Inc., Genentech, Inc., F. Hoffman-La Roche Ltd., Carrick Therapeutics Limited, and Bayer AG. The company was founded in 2013 and is based in New Haven, Connecticut.
Pioneering Therapies | Arvinas leads in protein degradation therapeutics, with promising candidates for breast and prostate cancer in advanced clinical trials |
Strategic Alliances | Partnerships with Pfizer and Novartis provide financial support and commercial expertise, potentially accelerating market entry for key therapies |
Financial Outlook | Despite ongoing losses, Arvinas maintains a strong cash position extending into 2027, with analyst price targets ranging from $48 to $90 |
Market Potential | Explore Arvinas' competitive edge in large oncology markets, balancing innovative treatments against established players and regulatory challenges |
Metrics to compare | ARVN | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipARVNPeersSector | |
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P/E Ratio | −5.8x | −5.9x | −0.6x | |
PEG Ratio | −0.30 | 0.07 | 0.00 | |
Price/Book | 3.0x | 2.8x | 2.6x | |
Price / LTM Sales | 11.1x | 1.9x | 3.2x | |
Upside (Analyst Target) | 135.7% | 92.9% | 44.6% | |
Fair Value Upside | Unlock | 16.9% | 7.3% | Unlock |